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Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome
BACKGROUND: Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) mutations are a genetic risk factor for Crohn disease. Ileocecal resection is the most often performed surgery in Crohn disease. We investigated the effect of Nod2 knockout (KO) status on anastomotic healing after exte...
Autores principales: | Witte, Maria, Reiner, Johannes, Bannert, Karen, Jaster, Robert, Maschmeier, Christian, Schafmayer, Clemens, Lamprecht, Georg, Berlin, Peggy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376130/ https://www.ncbi.nlm.nih.gov/pubmed/33555306 http://dx.doi.org/10.1093/ibd/izab022 |
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