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Population pharmacokinetic analysis of dupilumab in adult and adolescent patients with asthma

A population pharmacokinetic model was developed using data from healthy subjects and patients with moderate‐to‐severe asthma receiving intravenous or subcutaneous dupilumab doses. A total of nine phase I to phase III studies were pooled (202 healthy subjects and 1912 patients with asthma including...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Gao, Yue, Li, Meng, Xu, Christine, Davis, John D., Kanamaluru, Vanaja, Lu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376131/
https://www.ncbi.nlm.nih.gov/pubmed/34313019
http://dx.doi.org/10.1002/psp4.12667