Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes

Chronic infection with HCV is manifested by dysregulation of innate immune responses and impaired T cell function at multiple levels. These changes may impact susceptibility to other infections, responsiveness to antiviral therapies, vaccine responsiveness, and development of complications such as h...

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Detalles Bibliográficos
Autores principales: Burchill, Matthew A., Salomon, Matthew P., Golden-Mason, Lucy, Wieland, Amanda, Maretti-Mira, Ana C., Gale, Michael, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376199/
https://www.ncbi.nlm.nih.gov/pubmed/34370798
http://dx.doi.org/10.1371/journal.ppat.1009799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376199/
https://www.ncbi.nlm.nih.gov/pubmed/34370798
http://dx.doi.org/10.1371/journal.ppat.1009799

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