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Drosophila H2Av negatively regulates the activity of the IMD pathway via facilitating Relish SUMOylation
Insects depend on the innate immune response for defense against a wide array of pathogens. Central to Drosophila immunity are antimicrobial peptides (AMPs), released into circulation when pathogens trigger either of the two widely studied signal pathways, Toll or IMD. The Toll pathway responds to i...
Autores principales: | Tang, Ruijuan, Huang, Wuren, Guan, Jingmin, Liu, Qiuning, Beerntsen, Brenda T., Ling, Erjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376203/ https://www.ncbi.nlm.nih.gov/pubmed/34370736 http://dx.doi.org/10.1371/journal.pgen.1009718 |
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