Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data

Over the last decade the availability of SNP-trait associations from genome-wide association studies has led to an array of methods for performing Mendelian randomization studies using only summary statistics. A common feature of these methods, besides their intuitive simplicity, is the ability to c...

Descripción completa

Detalles Bibliográficos
Autores principales: Barry, Ciarrah, Liu, Junxi, Richmond, Rebecca, Rutter, Martin K., Lawlor, Deborah A., Dudbridge, Frank, Bowden, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376220/
https://www.ncbi.nlm.nih.gov/pubmed/34370750
http://dx.doi.org/10.1371/journal.pgen.1009703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376220/
https://www.ncbi.nlm.nih.gov/pubmed/34370750
http://dx.doi.org/10.1371/journal.pgen.1009703

Ejemplares similares