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Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

Morphogen signaling proteins disperse across tissues to activate signal transduction in target cells. We investigated dispersion of Hedgehog (Hh), Wnt homolog Wingless (Wg), and Bone morphogenic protein homolog Decapentaplegic (Dpp) in the Drosophila wing imaginal disc. We discovered that delivery o...

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Detalles Bibliográficos
Autores principales: Hatori, Ryo, Wood, Brent M, Oliveira Barbosa, Guilherme, Kornberg, Thomas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376250/
https://www.ncbi.nlm.nih.gov/pubmed/34292155
http://dx.doi.org/10.7554/eLife.71744