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GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

For a sperm to successfully fertilize an egg, it must first undergo capacitation in the female reproductive tract and later undergo acrosomal reaction (AR) upon encountering an egg surrounded by its vestment. How premature AR is avoided despite rapid surges in signaling cascades during capacitation...

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Detalles Bibliográficos
Autores principales: Reynoso, Sequoyah, Castillo, Vanessa, Katkar, Gajanan Dattatray, Lopez-Sanchez, Inmaculada, Taheri, Sahar, Espinoza, Celia, Rohena, Cristina, Sahoo, Debashis, Gagneux, Pascal, Ghosh, Pradipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376251/
https://www.ncbi.nlm.nih.gov/pubmed/34409938
http://dx.doi.org/10.7554/eLife.69160