Ruxolitinib plus extracorporeal photopheresis (ECP) for steroid refractory acute graft-versus-host disease of lower GI-tract after allogeneic stem cell transplantation leads to increased regulatory T cell level

Acute graft-versus-host disease (aGVHD) is a serious complication after stem cell transplantation and is associated with high non-relapse mortality. If steroid treatment as first-line therapeutic approach fails, treatment options are limited. In retrospective studies, ruxolitinib, a selective Janus...

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Detalles Bibliográficos
Autores principales: Modemann, Franziska, Ayuk, Francis, Wolschke, Christine, Christopeit, Maximilian, Janson, Dietlinde, von Pein, Ute-Marie, Kröger, Nicolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376644/
https://www.ncbi.nlm.nih.gov/pubmed/32447349
http://dx.doi.org/10.1038/s41409-020-0952-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376644/
https://www.ncbi.nlm.nih.gov/pubmed/32447349
http://dx.doi.org/10.1038/s41409-020-0952-z

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