Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets

The identification of cancer-specific vulnerability genes is one of the most promising approaches for developing more effective and less toxic cancer treatments. Cancer genomes exhibit thousands of changes in DNA methylation and gene expression, with the vast majority likely to be passenger changes....

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Detalles Bibliográficos
Autores principales: Schwalbe, Edward C., H, Lalchungnunga, Lafta, Fadhel, Barrow, Timothy M., Strathdee, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376645/
https://www.ncbi.nlm.nih.gov/pubmed/34230614
http://dx.doi.org/10.1038/s41388-021-01923-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376645/
https://www.ncbi.nlm.nih.gov/pubmed/34230614
http://dx.doi.org/10.1038/s41388-021-01923-1

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