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Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets
The identification of cancer-specific vulnerability genes is one of the most promising approaches for developing more effective and less toxic cancer treatments. Cancer genomes exhibit thousands of changes in DNA methylation and gene expression, with the vast majority likely to be passenger changes....
Autores principales: | Schwalbe, Edward C., H, Lalchungnunga, Lafta, Fadhel, Barrow, Timothy M., Strathdee, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376645/ https://www.ncbi.nlm.nih.gov/pubmed/34230614 http://dx.doi.org/10.1038/s41388-021-01923-1 |
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