Patients with obstructive sleep apnea have suppressed levels of soluble cytokine receptors involved in neurodegenerative disease, but normal levels with airways therapy

PURPOSE: Obstructive sleep apnea (OSA) results in systemic intermittent hypoxia. By one model, hypoxic stress signaling in OSA patients alters the levels of inflammatory soluble cytokines TNF and IL6, damages the blood brain barrier, and activates microglial targeting of neuronal cell death to incre...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Meagher, Richard B., Ambati, Suresh, Ma, Ping, Phillips, Bradley G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Basic Science • Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376707/
https://www.ncbi.nlm.nih.gov/pubmed/33037528
http://dx.doi.org/10.1007/s11325-020-02205-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376707/
https://www.ncbi.nlm.nih.gov/pubmed/33037528
http://dx.doi.org/10.1007/s11325-020-02205-y

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