Auto-inhibitory intramolecular S5/S6 interaction in the TRPV6 channel regulates breast cancer cell migration and invasion

TRPV6, a Ca-selective channel, is abundantly expressed in the placenta, intestine, kidney and bone marrow. TRPV6 is vital to Ca homeostasis and its defective expression or function is linked to transient neonatal hyperparathyroidism, Lowe syndrome/Dent disease, renal stone, osteoporosis and cancers....

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Detalles Bibliográficos
Autores principales: Cai, Ruiqi, Wang, Lingyun, Liu, Xiong, Michalak, Marek, Tang, Jingfeng, Peng, Ji-Bin, Chen, Xing-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376870/
https://www.ncbi.nlm.nih.gov/pubmed/34413465
http://dx.doi.org/10.1038/s42003-021-02521-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376870/
https://www.ncbi.nlm.nih.gov/pubmed/34413465
http://dx.doi.org/10.1038/s42003-021-02521-3

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