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Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading

During duration spaceflight, or after their return to earth, astronauts have often suffered from gait instability and cerebellar ataxia. Here, we use a mouse model of hindlimb unloading (HU) to explore a mechanism of how reduced hindlimb burden may contribute to motor deficits. The results showed th...

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Detalles Bibliográficos
Autores principales: Yao, Dandan, He, Qingyuan, Bai, Shangying, Zhao, Hang, Yang, Jun, Cui, Dehua, Yu, Yan, Fei, Xuechao, Mei, Yufei, Cheng, Ye, Yan, Shi, Huang, Nayan, Di, Yalan, Cai, Xianjie, Wang, Rui, Gao, Yajuan, Cheng, Fangxiao, Zhao, Shengjie, Yang, Xu, Cai, Xiang, Han, Hongbin, Lyu, Jihui, Tong, Zhiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376875/
https://www.ncbi.nlm.nih.gov/pubmed/34413463
http://dx.doi.org/10.1038/s42003-021-02448-9