Protein or ribonucleoprotein-mediated blocking of recombinase polymerase amplification enables the discrimination of nucleotide and epigenetic differences between cell populations

Isothermal DNA amplification, such as recombinase polymerase amplification (RPA), is well suited for point-of-care testing (POCT) as it does not require lengthy thermal cycling. By exploiting DNA amplification at low temperatures that do not denature heat-sensitive molecules such as proteins, we hav...

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Detalles Bibliográficos
Autores principales: Fujita, Toshitsugu, Nagata, Shoko, Fujii, Hodaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376914/
https://www.ncbi.nlm.nih.gov/pubmed/34413466
http://dx.doi.org/10.1038/s42003-021-02503-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376914/
https://www.ncbi.nlm.nih.gov/pubmed/34413466
http://dx.doi.org/10.1038/s42003-021-02503-5

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