14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites

Death-associated protein kinase 2 (DAPK2) is a CaM-regulated Ser/Thr protein kinase, involved in apoptosis, autophagy, granulocyte differentiation and motility regulation, whose activity is controlled by autoinhibition, autophosphorylation, dimerization and interaction with scaffolding proteins 14-3...

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Detalles Bibliográficos
Autores principales: Horvath, Matej, Petrvalska, Olivia, Herman, Petr, Obsilova, Veronika, Obsil, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376927/
https://www.ncbi.nlm.nih.gov/pubmed/34413451
http://dx.doi.org/10.1038/s42003-021-02518-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376927/
https://www.ncbi.nlm.nih.gov/pubmed/34413451
http://dx.doi.org/10.1038/s42003-021-02518-y

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