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14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites
Death-associated protein kinase 2 (DAPK2) is a CaM-regulated Ser/Thr protein kinase, involved in apoptosis, autophagy, granulocyte differentiation and motility regulation, whose activity is controlled by autoinhibition, autophosphorylation, dimerization and interaction with scaffolding proteins 14-3...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376927/ https://www.ncbi.nlm.nih.gov/pubmed/34413451 http://dx.doi.org/10.1038/s42003-021-02518-y |