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Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome

The human skin has a highly developed extracellular matrix (ECM) that is vital for proper skin functioning, its 3D architecture playing a pivotal role in support and guidance of resident and invading cells. To establish relevant in vitro models mimicking the complex design observed in vivo, scaffold...

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Detalles Bibliográficos
Autores principales: Vu, Bich, Souza, Glauco R., Dengjel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377039/
https://www.ncbi.nlm.nih.gov/pubmed/34435183
http://dx.doi.org/10.1016/j.mbplus.2021.100066