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Translational control by DHX36 binding to 5′UTR G-quadruplex is essential for muscle stem-cell regenerative functions

Skeletal muscle has a remarkable ability to regenerate owing to its resident stem cells (also called satellite cells, SCs). SCs are normally quiescent; when stimulated by damage, they activate and expand to form new fibers. The mechanisms underlying SC proliferative progression remain poorly underst...

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Detalles Bibliográficos
Autores principales: Chen, Xiaona, Yuan, Jie, Xue, Guang, Campanario, Silvia, Wang, Di, Wang, Wen, Mou, Xi, Liew, Shiau Wei, Umar, Mubarak Ishaq, Isern, Joan, Zhao, Yu, He, Liangqiang, Li, Yuying, Mann, Christopher J., Yu, Xiaohua, Wang, Lei, Perdiguero, Eusebio, Chen, Wei, Xue, Yuanchao, Nagamine, Yoshikuni, Kwok, Chun Kit, Sun, Hao, Muñoz-Cánoves, Pura, Wang, Huating
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377060/
https://www.ncbi.nlm.nih.gov/pubmed/34413292
http://dx.doi.org/10.1038/s41467-021-25170-w