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Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling

BACKGROUND AND AIMS: Nonalcoholic steatohepatitis is rapidly becoming the leading cause of liver failure and indication for liver transplantation. Hepatic inflammation is a key feature of NASH but the immune pathways involved in this process are poorly understood. B lymphocytes are cells of the adap...

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Detalles Bibliográficos
Autores principales: Barrow, Fanta, Khan, Saad, Fredrickson, Gavin, Wang, Haiguang, Dietsche, Katrina, Parthiban, Preethy, Robert, Sacha, Kaiser, Thomas, Winer, Shawn, Herman, Adam, Adeyi, Oyedele, Mouzaki, Marialena, Khoruts, Alexander, Hogquist, Kristin A., Staley, Christopher, Winer, Daniel A., Revelo, Xavier S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377092/
https://www.ncbi.nlm.nih.gov/pubmed/33609303
http://dx.doi.org/10.1002/hep.31755