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Microbiota‐Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling
BACKGROUND AND AIMS: Nonalcoholic steatohepatitis is rapidly becoming the leading cause of liver failure and indication for liver transplantation. Hepatic inflammation is a key feature of NASH but the immune pathways involved in this process are poorly understood. B lymphocytes are cells of the adap...
Autores principales: | Barrow, Fanta, Khan, Saad, Fredrickson, Gavin, Wang, Haiguang, Dietsche, Katrina, Parthiban, Preethy, Robert, Sacha, Kaiser, Thomas, Winer, Shawn, Herman, Adam, Adeyi, Oyedele, Mouzaki, Marialena, Khoruts, Alexander, Hogquist, Kristin A., Staley, Christopher, Winer, Daniel A., Revelo, Xavier S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377092/ https://www.ncbi.nlm.nih.gov/pubmed/33609303 http://dx.doi.org/10.1002/hep.31755 |
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