Non-Extensive Fragmentation of Natural Products and Pharmacophore-Based Virtual Screening as a Practical Approach to Identify Novel Promising Chemical Scaffolds

Fragment-based drug design (FBDD) and pharmacophore modeling have proven to be efficient tools to discover novel drugs. However, these approaches may become limited if the collection of fragments is highly repetitive, poorly diverse, or excessively simple. In this article, combining pharmacophore mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Vásquez, Andrés Felipe, Muñoz, Alejandro Reyes, Duitama, Jorge, González Barrios, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377161/
https://www.ncbi.nlm.nih.gov/pubmed/34422762
http://dx.doi.org/10.3389/fchem.2021.700802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377161/
https://www.ncbi.nlm.nih.gov/pubmed/34422762
http://dx.doi.org/10.3389/fchem.2021.700802

Ejemplares similares