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Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis

Although studies in oncology have well explored the pharmacological effects of Birc5, little is known about its role in allogeneic T-cell responses. Therefore, the present study used a mouse model of acute heart allograft rejection to investigate the protective effect and mechanism of conditional kn...

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Detalles Bibliográficos
Autores principales: Xu, Heng, Yu, Jizhang, Cui, Jikai, Chen, Zhang, Zhang, Xi, Zou, Yanqiang, Du, Yifan, Li, Yuan, Le, Sheng, Jiang, Lang, Xia, Jiahong, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377163/
https://www.ncbi.nlm.nih.gov/pubmed/34421916
http://dx.doi.org/10.3389/fimmu.2021.710904