Cargando…

The Impact of Nrf2 Silencing on Nrf2-PD-L1 Axis to Overcome Oxaliplatin Resistance and Migration in Colon Cancer Cells

BACKGROUND: Nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a key role in promoting chemoresistance in various cancers. PD-L1 is one of the downstream targets of the Nrf2 signaling pathway. This molecule has some beneficial impacts on tumors growth by inhibition of the immune system. This s...

Descripción completa

Detalles Bibliográficos
Autores principales: Payandeh, Zahra, Pirpour Tazehkand, Abbas, Mansoori, Behzad, Khaze, Vahid, Asadi, Milad, Baradaran, Behzad, Samadi, Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377400/
https://www.ncbi.nlm.nih.gov/pubmed/34484640
http://dx.doi.org/10.18502/ajmb.v13i3.6371