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An Integrated Bioinformatics Analysis of the Potential Regulatory Effects of miR-21 on T-cell Related Target Genes in Multiple Sclerosis

BACKGROUND: Overexpression of miR-21 is a characteristic feature of patients with Multiple Sclerosis (MS) and is involved in gene regulation and the expression enhancement of pro-inflammatory factors including IFNγ and TNF-α following stimulation of T-cells via the T Cell Receptor (TCR). In this stu...

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Detalles Bibliográficos
Autores principales: Manian, Mostafa, Sohrabi, Ehsan, Eskandari, Nahid, Assarehzadegan, Mohammad-Ali, Ferns, Gordon A., Nourbakhsh, Mitra, Jazayeri, Mir Hadi, Nedaeinia, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377402/
https://www.ncbi.nlm.nih.gov/pubmed/34484645
http://dx.doi.org/10.18502/ajmb.v13i3.6364