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An Integrated Bioinformatics Analysis of the Potential Regulatory Effects of miR-21 on T-cell Related Target Genes in Multiple Sclerosis
BACKGROUND: Overexpression of miR-21 is a characteristic feature of patients with Multiple Sclerosis (MS) and is involved in gene regulation and the expression enhancement of pro-inflammatory factors including IFNγ and TNF-α following stimulation of T-cells via the T Cell Receptor (TCR). In this stu...
Autores principales: | Manian, Mostafa, Sohrabi, Ehsan, Eskandari, Nahid, Assarehzadegan, Mohammad-Ali, Ferns, Gordon A., Nourbakhsh, Mitra, Jazayeri, Mir Hadi, Nedaeinia, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377402/ https://www.ncbi.nlm.nih.gov/pubmed/34484645 http://dx.doi.org/10.18502/ajmb.v13i3.6364 |
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