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Designing a Strategy for pH Control to Improve CHO Cell Productivity in Bioreactor
BACKGROUND: Drastic pH drop is a common consequence of scaling up a mammalian cell culture process, where it may affect the final performance of cell culture. Although CO(2) sparging and base addition are used as common approaches for pH control, these strategies are not necessarily successful in la...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377406/ https://www.ncbi.nlm.nih.gov/pubmed/34484641 http://dx.doi.org/10.18502/ajmb.v13i3.6365 |