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Designing a Strategy for pH Control to Improve CHO Cell Productivity in Bioreactor

BACKGROUND: Drastic pH drop is a common consequence of scaling up a mammalian cell culture process, where it may affect the final performance of cell culture. Although CO(2) sparging and base addition are used as common approaches for pH control, these strategies are not necessarily successful in la...

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Detalles Bibliográficos
Autores principales: Ahleboot, Zohreh, Khorshidtalab, Mahdi, Motahari, Paria, Mahboudi, Rasoul, Arjmand, Razieh, Mokarizadeh, Aram, Maleknia, Shayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377406/
https://www.ncbi.nlm.nih.gov/pubmed/34484641
http://dx.doi.org/10.18502/ajmb.v13i3.6365