Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice

Proper functioning of the cerebellum is crucial to motor balance and coordination in adult mammals. Purkinje cells (PCs), the sole output neurons of the cerebellar cortex, play essential roles in cerebellar motor function. Tripartite motif-containing protein 32 (TRIM32) is an E3 ubiquitin ligase tha...

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Detalles Bibliográficos
Autores principales: Zhu, Jian-Wei, Jia, Wei-Qiang, Zhou, Hui, Li, Yi-Fei, Zou, Ming-Ming, Wang, Zhao-Tao, Wu, Bing-Shan, Xu, Ru-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377415/
https://www.ncbi.nlm.nih.gov/pubmed/34421574
http://dx.doi.org/10.3389/fnagi.2021.697494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377415/
https://www.ncbi.nlm.nih.gov/pubmed/34421574
http://dx.doi.org/10.3389/fnagi.2021.697494

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