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Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice
Proper functioning of the cerebellum is crucial to motor balance and coordination in adult mammals. Purkinje cells (PCs), the sole output neurons of the cerebellar cortex, play essential roles in cerebellar motor function. Tripartite motif-containing protein 32 (TRIM32) is an E3 ubiquitin ligase tha...
Autores principales: | Zhu, Jian-Wei, Jia, Wei-Qiang, Zhou, Hui, Li, Yi-Fei, Zou, Ming-Ming, Wang, Zhao-Tao, Wu, Bing-Shan, Xu, Ru-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377415/ https://www.ncbi.nlm.nih.gov/pubmed/34421574 http://dx.doi.org/10.3389/fnagi.2021.697494 |
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