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TLE4 Is a Critical Mediator of Osteoblast and Runx2-Dependent Bone Development

Healthy bone homeostasis hinges upon a delicate balance and regulation of multiple processes that contribute to bone development and metabolism. While examining hematopoietic regulation by Tle4, we have uncovered a previously unappreciated role of Tle4 on bone calcification using a novel Tle4 null m...

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Detalles Bibliográficos
Autores principales: Shin, Thomas H., Theodorou, Evangelos, Holland, Carl, Yamin, Rae’e, Raggio, Cathleen L., Giampietro, Philip F., Sweetser, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377417/
https://www.ncbi.nlm.nih.gov/pubmed/34422801
http://dx.doi.org/10.3389/fcell.2021.671029