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An exploratory first‐in‐man study to investigate the pharmacokinetics and safety of liposomal dexamethasone at a 2‐ and 1‐week interval in patients with metastatic castration resistant prostate cancer

Dexamethasone has antitumor activity in metastatic castration resistant prostate cancer (mCRPC). We aimed to investigate intravenous liposome‐encapsulated dexamethasone disodium phosphate (liposomal dexamethasone) administration in mCRPC patients. In this exploratory first‐in‐man study, patients in...

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Detalles Bibliográficos
Autores principales: Vrouwe, Josephina P. M., Kamerling, Ingrid M. C., van Esdonk, Michiel J., Metselaar, Josbert M., Stuurman, Frederik E., van der Pluijm, Gabri, Burggraaf, Jacobus, Osanto, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377443/
https://www.ncbi.nlm.nih.gov/pubmed/34414692
http://dx.doi.org/10.1002/prp2.845