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Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue

Psychiatric stress has been associated with accelerated epigenetic aging (i.e., when estimates of cellular age based on DNA methylation exceed chronological age) in both blood and brain tissue. Little is known about the downstream biological effects of accelerated epigenetic age on gene expression....

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Detalles Bibliográficos
Autores principales: Wolf, Erika J., Zhao, Xiang, Hawn, Sage E., Morrison, Filomene G., Zhou, Zhenwei, Fein-Schaffer, Dana, Huber, Bertrand, Miller, Mark W., Logue, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377489/
https://www.ncbi.nlm.nih.gov/pubmed/34458511
http://dx.doi.org/10.1016/j.ynstr.2021.100371