Cargando…
Impact of Serum Proteins on the Uptake and RNAi Activity of GalNAc-Conjugated siRNAs
Serum protein interactions are evaluated during the drug development process since they determine the free drug concentration in blood and thereby can influence the drug's pharmacokinetic and pharmacodynamic properties. While the impact of serum proteins on the disposition of small molecules is...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mary Ann Liebert, Inc., publishers
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377513/ https://www.ncbi.nlm.nih.gov/pubmed/33861634 http://dx.doi.org/10.1089/nat.2020.0919 |