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Delivery of membrane impermeable molecules to primary mouse T lymphocytes

The pore-forming toxin streptolysin-O (SLO) enables intracellular delivery of molecules up to 100 kDa and has been used for short-term delivery of membrane-impermeable substances to assess their effects on cellular activities. A limitation of this technique is the loss of intracellular components an...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Li, Ming O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377589/
https://www.ncbi.nlm.nih.gov/pubmed/34458872
http://dx.doi.org/10.1016/j.xpro.2021.100757