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Delivery of membrane impermeable molecules to primary mouse T lymphocytes
The pore-forming toxin streptolysin-O (SLO) enables intracellular delivery of molecules up to 100 kDa and has been used for short-term delivery of membrane-impermeable substances to assess their effects on cellular activities. A limitation of this technique is the loss of intracellular components an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377589/ https://www.ncbi.nlm.nih.gov/pubmed/34458872 http://dx.doi.org/10.1016/j.xpro.2021.100757 |