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A T-cell-based immunogenicity protocol for evaluating human antigen-specific responses

Determining the antigen specificities of the endogenous T-cell repertoire is important for screening naturally occurring or therapy-induced T-cell immunity and may help identify novel targets for T-cell-based therapies. Here, we describe a rapid, sensitive, and high-throughput protocol for expanding...

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Detalles Bibliográficos
Autores principales: Cimen Bozkus, Cansu, Blazquez, Ana Belen, Enokida, Tomohiro, Bhardwaj, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377590/
https://www.ncbi.nlm.nih.gov/pubmed/34458873
http://dx.doi.org/10.1016/j.xpro.2021.100758