Conservation of S20 as an Ineffective and Disposable IFNγ-Inducing Determinant of Plasmodium Sporozoites Indicates Diversion of Cellular Immunity

Despite many decades of research to develop a malaria vaccine, only one vaccine candidate has been explored in pivotal phase III clinical trials. This candidate subunit vaccine consists of a portion of a single Plasmodium antigen, circumsporozoite protein (CSP). This antigen was initially identified...

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Detalles Bibliográficos
Autores principales: Hon, Calvin, Friesen, Johannes, Ingmundson, Alyssa, Scheppan, Diana, Hafalla, Julius C. R., Müller, Katja, Matuschewski, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377727/
https://www.ncbi.nlm.nih.gov/pubmed/34421862
http://dx.doi.org/10.3389/fmicb.2021.703804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377727/
https://www.ncbi.nlm.nih.gov/pubmed/34421862
http://dx.doi.org/10.3389/fmicb.2021.703804

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