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Gremlin2 Activates Fibroblasts to Promote Pulmonary Fibrosis Through the Bone Morphogenic Protein Pathway

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease causing unremitting extracellular matrix deposition. Transforming growth factor-β (TGF-β) superfamily involves bone morphogenetic proteins (BMPs) and TGF-β, and the balance between the activation of TGF-β-dependent SMADs (Smad2/3) and...

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Detalles Bibliográficos
Autores principales: Huan, Caijuan, Xu, Wangting, Liu, Yaru, Ruan, Kexin, Shi, Yueli, Cheng, Hongqiang, Zhang, Xue, Ke, Yuehai, Zhou, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377751/
https://www.ncbi.nlm.nih.gov/pubmed/34422900
http://dx.doi.org/10.3389/fmolb.2021.683267