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Computational Study on DNA Repair: The Roles of Electrostatic Interactions Between Uracil-DNA Glycosylase (UDG) and DNA

Uracil-DNA glycosylase (UDG) is one of the most important base excision repair (BER) enzymes involved in the repair of uracil-induced DNA lesion by removing uracil from the damaged DNA. Uracil in DNA may occur due to cytosine deamination or deoxy uridine monophosphate (dUMP) residue misincorporation...

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Detalles Bibliográficos
Autores principales: Xie, Yixin, Karki, Chitra B., Chen, Jiawei, Liu, Dongfang, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377759/
https://www.ncbi.nlm.nih.gov/pubmed/34422909
http://dx.doi.org/10.3389/fmolb.2021.718587