Cargando…

Computational Study on DNA Repair: The Roles of Electrostatic Interactions Between Uracil-DNA Glycosylase (UDG) and DNA

Uracil-DNA glycosylase (UDG) is one of the most important base excision repair (BER) enzymes involved in the repair of uracil-induced DNA lesion by removing uracil from the damaged DNA. Uracil in DNA may occur due to cytosine deamination or deoxy uridine monophosphate (dUMP) residue misincorporation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yixin, Karki, Chitra B., Chen, Jiawei, Liu, Dongfang, Li, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377759/ https://www.ncbi.nlm.nih.gov/pubmed/34422909 http://dx.doi.org/10.3389/fmolb.2021.718587

Ejemplares similares

Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity
por: Chembazhi, Ullas Valiya, et al.
Publicado: (2017)

Colorimetric detection of SARS-CoV-2 by uracil-DNA glycosylase (UDG) reverse transcription loop-mediated isothermal amplification (RT-LAMP)
por: Lai, Meng Yee, et al.
Publicado: (2022)

A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily
por: Sang, Pau Biak, et al.
Publicado: (2015)

Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase
por: Schormann, N., et al.
Publicado: (2013)

Uracil–DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms
por: Pettersen, Henrik Sahlin, et al.
Publicado: (2007)

Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
por: Kachhap, Sushant, et al.
Publicado: (2004)

Crystal structure of mimivirus uracil-DNA glycosylase
por: Kwon, Eunju, et al.
Publicado: (2017)

Mitochondrial DNA Repair in an Arabidopsis thaliana Uracil N-Glycosylase Mutant
por: Wynn, Emily, et al.
Publicado: (2020)

Development of uracil-DNA-glycosylase-supplemented loop-mediated isothermal amplification coupled with nanogold probe (UDG-LAMP-AuNP) for specific detection of Pseudomonas aeruginosa
por: Manajit, Orapan, et al.
Publicado: (2018)

Protein p56 from the Bacillus subtilis phage ϕ29 inhibits DNA-binding ability of uracil-DNA glycosylase
por: Serrano-Heras, Gemma, et al.
Publicado: (2007)

Measurement of nanoscale DNA translocation by uracil DNA glycosylase in human cells
por: Esadze, Alexandre, et al.
Publicado: (2017)

Uracil-DNA glycosylase efficiency is modulated by substrate rigidity
por: Orndorff, Paul B., et al.
Publicado: (2023)

Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase
por: Schormann, Norbert, et al.
Publicado: (2015)

The mesophilic archaeon Methanosarcina acetivorans counteracts uracil in DNA with multiple enzymes: EndoQ, ExoIII, and UDG
por: Shiraishi, Miyako, et al.
Publicado: (2018)

Correlated Mutation in the Evolution of Catalysis in Uracil DNA Glycosylase Superfamily
por: Xia, Bo, et al.
Publicado: (2017)

Advanced uracil DNA glycosylase-supplemented real-time reverse transcription loop-mediated isothermal amplification (UDG-rRT-LAMP) method for universal and specific detection of Tembusu virus
por: Tang, Yi, et al.
Publicado: (2016)

Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair
por: Bulgar, A D, et al.
Publicado: (2012)

Uracil–DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil
por: Sarno, Antonio, et al.
Publicado: (2019)

A structural determinant in the uracil DNA glycosylase superfamily for the removal of uracil from adenine/uracil base pairs
por: Lee, Dong-Hoon, et al.
Publicado: (2015)

Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo
por: Wu, Di, et al.
Publicado: (2014)

Monitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensors
por: Ono, Toshikazu, et al.
Publicado: (2013)

Editorial: The repair of DNA–protein crosslinks
por: Sun, Yilun, et al.
Publicado: (2023)

Mechanisms and Regulation of DNA-Protein Crosslink Repair During DNA Replication by SPRTN Protease
por: Perry, Megan, et al.
Publicado: (2022)

StructureMan: A Structure Manipulation Tool to Study Large Scale Biomolecular Interactions
por: Xian, Yuejiao, et al.
Publicado: (2021)

DR0022 from Deinococcus radiodurans is an acid uracil‐DNA glycosylase
por: Li, Jing, et al.
Publicado: (2022)

DNA glycosylases: in DNA repair and beyond
por: Jacobs, Angelika L., et al.
Publicado: (2011)

The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
por: Jimeno, Sonia, et al.
Publicado: (2021)

Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54
por: Strang, Blair L., et al.
Publicado: (2010)

DNA Repair and Signaling in Immune-Related Cancer Therapy
por: Kakoti, Sangeeta, et al.
Publicado: (2020)

N(6)-Methyladenosine, DNA Repair, and Genome Stability
por: Qu, Fei, et al.
Publicado: (2021)

Editorial: Cancer Therapeutics: Targeting DNA Repair Pathways
por: Suraweera, Amila, et al.
Publicado: (2022)

N-terminal domain of human uracil DNA glycosylase (hUNG2) promotes targeting to uracil sites adjacent to ssDNA–dsDNA junctions
por: Weiser, Brian P, et al.
Publicado: (2018)

Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
por: Schormann, Norbert, et al.
Publicado: (2007)

Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription
por: Fenard, David, et al.
Publicado: (2009)

Uracil DNA glycosylase 2 negatively regulates HIV-1 LTR transcription
por: Fenard, David, et al.
Publicado: (2009)

Uracil DNA N-Glycosylase Promotes Assembly of Human Centromere Protein A
por: Zeitlin, Samantha G., et al.
Publicado: (2011)

A Mutant of Uracil DNA Glycosylase That Distinguishes between Cytosine and 5-Methylcytosine
por: Kimber, Scott T., et al.
Publicado: (2014)

Architecturally diverse proteins converge on an analogous mechanism to inactivate Uracil-DNA glycosylase
por: Cole, Ambrose R., et al.
Publicado: (2013)

Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor
por: Wang, Hao-Ching, et al.
Publicado: (2014)

Cadmium(II) inhibition of human uracil-DNA glycosylase by catalytic water supplantation
por: Gokey, Trevor, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5bt508q61i6k2g85e77fla98bd