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Targeted Next-Generation Sequencing of Circulating Tumor DNA, Bone Marrow, and Peripheral Blood Mononuclear Cells in Pediatric AML

BACKGROUND: The aim of the study was to validate the diagnostic role of circulating tumor DNA (ctDNA) in genetics aberration on the basis of next-generation sequencing (NGS) in pediatric acute myeloid leukemia (AML). METHODS: Bone marrow (BM) and peripheral blood (PB) were collected from 20 AML chil...

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Detalles Bibliográficos
Autores principales: Ruan, Min, Liu, Lipeng, Qi, Benquan, Chen, Xiaoyan, Chang, Lixian, Zhang, Aoli, Liu, Fang, Wang, Shuchun, Liu, Xiaoming, Chen, Xiaojuan, Zhang, Li, Guo, Ye, Zou, Yao, Zhang, Yingchi, Chen, Yumei, Liu, LiXia, Cao, Shanbo, Lou, Feng, Wang, Chengcheng, Zhu, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377768/
https://www.ncbi.nlm.nih.gov/pubmed/34422630
http://dx.doi.org/10.3389/fonc.2021.666470