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Cooperation between liver-specific mutations of pten and tp53 genetically induces hepatocarcinogenesis in zebrafish

BACKGROUND: Liver cancer, mainly hepatocellular carcinoma, is one of the deadliest cancers worldwide and has a poor prognosis due to insufficient understanding of hepatocarcinogenesis. Previous studies have revealed that the mutations in PTEN and TP53 are the two most common genetic events in hepato...

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Detalles Bibliográficos
Autores principales: Luo, Juanjuan, Lu, Chunjiao, Feng, Meilan, Dai, Lu, Wang, Maya, Qiu, Yang, Zheng, Huilu, Liu, Yao, Li, Li, Tang, Bo, Xu, Chuan, Wang, Yajun, Yang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377946/
https://www.ncbi.nlm.nih.gov/pubmed/34416907
http://dx.doi.org/10.1186/s13046-021-02061-y