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Protective role of the alpha-1-antitrypsin in intervertebral disc degeneration

BACKGROUND: Intervertebral disc degeneration is a complex disease with high prevalence. It suggests that cell death, senescence, and extracellular matrix degradation are involved in the pathogenesis. Alpha-1 antitrypsin (AAT), a serine protease inhibitor, was previously correlated with inflammation-...

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Detalles Bibliográficos
Autores principales: Liu, Weikun, Wang, Yanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377970/
https://www.ncbi.nlm.nih.gov/pubmed/34416893
http://dx.doi.org/10.1186/s13018-021-02668-z