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Agmatine Alleviates Epileptic Seizures and Hippocampal Neuronal Damage by Inhibiting Gasdermin D-Mediated Pyroptosis

Background: Epilepsy is a common neurological disease, and neuroinflammation is one of the main contributors to epileptogenesis. Pyroptosis is a type of pro-inflammatory cell death that is related to epilepsy. Agmatine, has anti-inflammatory properties and exerts neuroprotective effects against seiz...

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Detalles Bibliográficos
Autores principales: Li, Xueying, Lin, Jiahe, Hua, Yingjie, Gong, Jiaoni, Ding, Siqi, Du, Yanru, Wang, Xinshi, Zheng, Rongyuan, Xu, Huiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378273/
https://www.ncbi.nlm.nih.gov/pubmed/34421582
http://dx.doi.org/10.3389/fphar.2021.627557