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Agmatine Alleviates Epileptic Seizures and Hippocampal Neuronal Damage by Inhibiting Gasdermin D-Mediated Pyroptosis
Background: Epilepsy is a common neurological disease, and neuroinflammation is one of the main contributors to epileptogenesis. Pyroptosis is a type of pro-inflammatory cell death that is related to epilepsy. Agmatine, has anti-inflammatory properties and exerts neuroprotective effects against seiz...
Autores principales: | Li, Xueying, Lin, Jiahe, Hua, Yingjie, Gong, Jiaoni, Ding, Siqi, Du, Yanru, Wang, Xinshi, Zheng, Rongyuan, Xu, Huiqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378273/ https://www.ncbi.nlm.nih.gov/pubmed/34421582 http://dx.doi.org/10.3389/fphar.2021.627557 |
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