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Spliceosomal component PRP-40 is a central regulator of microexon splicing

Microexons (≤27 nt) play critical roles in nervous system development and function but create unique challenges for the splicing machinery. The mechanisms of microexon regulation are therefore of great interest. We performed a genetic screen for alternative splicing regulators in the C. elegans nerv...

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Detalles Bibliográficos
Autores principales: Choudhary, Bikash, Marx, Olivia, Norris, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378409/
https://www.ncbi.nlm.nih.gov/pubmed/34348142
http://dx.doi.org/10.1016/j.celrep.2021.109464