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Genetic Analysis of DinG Family Helicase YoaA and Its Interaction with Replication Clamp Loader Protein HolC in Escherichia coli

The XP-D/DinG family of DNA helicases contributes to genomic stability in all three domains of life. Here, we investigate the role of one of these proteins, YoaA, of Escherichia coli. In E. coli, YoaA aids in tolerance to the nucleoside azidothymidine (AZT), a DNA replication inhibitor, and physical...

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Detalles Bibliográficos
Autores principales: Sutera, Vincent A., Sass, Thalia H., Leonard, Scott E., Wu, Lingling, Glass, David J., Giordano, Gabriela G., Zur, Yonatan, Lovett, Susan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378479/
https://www.ncbi.nlm.nih.gov/pubmed/34181484
http://dx.doi.org/10.1128/JB.00228-21