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Host genetic diversity drives variable central nervous system lesion distribution in chronic phase of Theiler’s Murine Encephalomyelitis Virus (TMEV) infection

Host genetic background is a significant driver of the variability in neurological responses to viral infection. Here, we leverage the genetically diverse Collaborative Cross (CC) mouse resource to better understand how chronic infection by Theiler’s Murine Encephalomyelitis Virus (TMEV) elicits div...

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Detalles Bibliográficos
Autores principales: Lawley, Koedi S., Rech, Raquel R., Elenwa, Faith, Han, Gang, Perez Gomez, Aracely A., Amstalden, Katia, Welsh, C. Jane, Young, Colin R., Threadgill, David W., Brinkmeyer-Langford, Candice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378701/
https://www.ncbi.nlm.nih.gov/pubmed/34415947
http://dx.doi.org/10.1371/journal.pone.0256370