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Determination of variable region sequences from hybridoma immunoglobulins that target Mycobacterium tuberculosis virulence factors

Mycobacterium tuberculosis (Mtb) infects one-quarter of the world’s population. Mtb and HIV coinfections enhance the comorbidity of tuberculosis (TB) and AIDS, accounting for one-third of all AIDS-associated mortalities. Humoral antibody to Mtb correlates with TB susceptibility, and engineering of M...

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Detalles Bibliográficos
Autores principales: Foreman, Hui-Chen Chang, Frank, Andrew, Stedman, Timothy T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378720/
https://www.ncbi.nlm.nih.gov/pubmed/34415957
http://dx.doi.org/10.1371/journal.pone.0256079