Cargando…

Determination of variable region sequences from hybridoma immunoglobulins that target Mycobacterium tuberculosis virulence factors

Mycobacterium tuberculosis (Mtb) infects one-quarter of the world’s population. Mtb and HIV coinfections enhance the comorbidity of tuberculosis (TB) and AIDS, accounting for one-third of all AIDS-associated mortalities. Humoral antibody to Mtb correlates with TB susceptibility, and engineering of M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foreman, Hui-Chen Chang, Frank, Andrew, Stedman, Timothy T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378720/ https://www.ncbi.nlm.nih.gov/pubmed/34415957 http://dx.doi.org/10.1371/journal.pone.0256079

Ejemplares similares

The application of hybridoma technology to the study of bovine immunoglobulins
por: Goldsby, R.A., et al.
Publicado: (1987)

When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions
por: Bradbury, Andrew R. M., et al.
Publicado: (2018)

CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells
por: Gall, Camille Le M., et al.
Publicado: (2023)

Synthesis of abnormal immunoglobulins by hybridomas from autoimmune "viable motheaten" mutant mice
Publicado: (1991)

Identification of Immunoglobulin Gene Sequences from a Small Read Number of mRNA-Seq Using Hybridomas
por: Kuniyoshi, Yuki, et al.
Publicado: (2016)

Pathogenicity and virulence of Mycobacterium tuberculosis
por: Rahlwes, Kathryn C., et al.
Publicado: (2023)

Production of autoreactive I region-restricted T cell hybridomas
Publicado: (1982)

Analysis of T cell hybridomas. IV. Characterization of inducible suppressor cell hybridomas
Publicado: (1983)

Virulence factors of the Mycobacterium tuberculosis complex
por: Forrellad, Marina A., et al.
Publicado: (2013)

Effects of Mycobacterium tuberculosis lineages and regions of difference (RD) virulence gene variation on tuberculosis recurrence
por: He, Chuanjiang, et al.
Publicado: (2022)

Comprehensive Determination of Mycobacterium tuberculosis and Nontuberculous Mycobacteria From Targeted Capture Sequencing
por: He, Ya, et al.
Publicado: (2020)

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas
Publicado: (1986)

How to make a hybridoma.
por: Lerner, E. A.
Publicado: (1981)

Hybridoma technology: is it still useful?
por: Moraes, Jane Zveiter, et al.
Publicado: (2021)

Convergence of two global regulators to coordinate expression of essential virulence determinants of Mycobacterium tuberculosis
por: Khan, Hina, et al.
Publicado: (2022)

High-Throughput Sequencing of Human Immunoglobulin Variable Regions with Subtype Identification
por: Schanz, Merle, et al.
Publicado: (2014)

γδ T cells response to Mycobacterium tuberculosis in pulmonary tuberculosis patients using preponderant complementary determinant region 3 sequence
por: Xi, Xueyan, et al.
Publicado: (2011)

Three T cell hybridomas do not contain detectable heavy chain variable gene transcripts
Publicado: (1983)

Genomic Sequencing Profiles of Mycobacterium tuberculosis in Mandalay Region, Myanmar
por: Phyu, Aye Nyein, et al.
Publicado: (2023)

Solubility evaluation of murine hybridoma antibodies
por: Spencer, Stacey, et al.
Publicado: (2012)

Differential determinants of virulence in two Mycobacterium tuberculosis Colombian clinical isolates of the LAM09 family
por: Baena, Andres, et al.
Publicado: (2019)

Editorial: Cellular and Molecular Mechanisms of Mycobacterium tuberculosis Virulence
por: Sun, Jianjun, et al.
Publicado: (2019)

Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
por: Malakar, Basanti, et al.
Publicado: (2023)

Use of Epstein-Barr virus-transformed B cell lines for the generation of immunoglobulin-producing human B cell hybridomas
Publicado: (1982)

Mycobacterium tuberculosis virulence inhibitors discovered by Mycobacterium marinum high-throughput screening
por: Tükenmez, Hasan, et al.
Publicado: (2019)

Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis
por: Omar, Shaheed V., et al.
Publicado: (2019)

The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
por: Matsuda, Fumihiko, et al.
Publicado: (1998)

DNA Sequence of Immunoglobulin Heavy Chain Variable Region Gene in Thyroid Lymphoma
por: Miwa, Hideaki, et al.
Publicado: (2001)

Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis
por: Singh, Mamta, et al.
Publicado: (2016)

Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency
Publicado: (1988)

Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells
por: Ramos-Martinez, Ana Gabriela, et al.
Publicado: (2019)

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization
Publicado: (1987)

A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis
por: Rajwani, Rahim, et al.
Publicado: (2022)

Efficient human-like antibody repertoire and hybridoma production in trans-chromosomic mice carrying megabase-sized human immunoglobulin loci
por: Satofuka, Hiroyuki, et al.
Publicado: (2022)

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages
por: Kim, Dae Young, et al.
Publicado: (2023)

Bioinformatic identification of Mycobacterium tuberculosis proteins likely to target host cell mitochondria: virulence factors?
por: Moreno-Altamirano, María Maximina Bertha, et al.
Publicado: (2012)

Comparison of Mycobacterium Tuberculosis Genomes Reveals Frequent Deletions in a 20 kb Variable Region in Clinical Isolates
por: Ho, Timothy B. L., et al.
Publicado: (2000)

Mycobacterium tuberculosis acg Gene Is Required for Growth and Virulence In Vivo
por: Hu, Yanmin, et al.
Publicado: (2011)

A novel peptide interferes with Mycobacterium tuberculosis virulence and survival
por: Samuchiwal, Sachin Kumar, et al.
Publicado: (2014)

A central role for aspartate in Mycobacterium tuberculosis physiology and virulence
por: Gouzy, Alexandre, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_odb35me53riu8jaqdp41dbg69v