IMRAS—Immunization with radiation-attenuated Plasmodium falciparum sporozoites by mosquito bite: Cellular immunity to sporozoites, CSP, AMA1, TRAP and CelTOS

BACKGROUND: Immunization with radiation-attenuated sporozoites (RAS) by mosquito bites provides >90% sterile protection against Plasmodium falciparum malaria in humans. We conducted a clinical trial based on data from previous RAS clinical trials that suggested that 800–1200 infected bites should...

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Detalles Bibliográficos
Autores principales: Sedegah, Martha, Hollingdale, Michael R., Ganeshan, Harini, Belmonte, Maria, Huang, Jun, Belmonte, Arnel, Inoue, Sandra, Velasco, Rachel, Hickey, Bradley, Teneza-Mora, Nimfa, Lumsden, Joanne, Reyes, Sharina, Banania, Jo Glenna, Reyes, Anatalio, Guzman, Ivelese, Richie, Thomas L., Epstein, Judith E., Villasante, Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378721/
https://www.ncbi.nlm.nih.gov/pubmed/34415964
http://dx.doi.org/10.1371/journal.pone.0256396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378721/
https://www.ncbi.nlm.nih.gov/pubmed/34415964
http://dx.doi.org/10.1371/journal.pone.0256396

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